Pancreatic Cancer Infographic: Pancreatic Cancer Facts and Figures By UPMC Hillman Cancer Center, April 26, 2015 Pancreatic cancer is caused by abnormal growth of the cells in the pancreas, a glandular organ behind the stomach. It is estimated that pancreatic cancer will affect one in 67 people in the U.S. in 2015. Due to the location, it is sometimes hard to diagnose in the early stages, making this one of the most deadly cancers. Some of the earliest signs of pancreatic cancer might be weight loss, abdominal or back pain, yellowing skin, or gallbladder enlargement. The main risk factors for pancreatic cancer include tobacco use, obesity, diabetes, and family history. Find out more information on pancreatic cancer care and treatment at UPMC Hillman Cancer Center.