The most common type of brain tumor, glioblastoma, is also the most aggressive \u2014 and hardest to treat.\nGlioblastoma is a fast-growing cancer that forms tumors on the supportive tissue of the brain. This disease most often affects adults and develops in the brain\u2019s frontal and temporal lobes.\nLearn more about glioblastoma on the UPMC Department of Neurosurgery website. Fill out the form to contact the UPMC Neurosurgery team.\nHighly malignant because its cells rapidly reproduce, glioblastoma tumors are remarkably difficult to remove, though some patients can undergo surgery.\nDoctors do not know the exact cause of glioblastoma.\nGlioblastoma Symptoms\nThe symptoms of glioblastoma can vary based on the location of the tumor. Some warning signs include:\n\nHeadaches\nConfusion\nSeizures\nNausea or vomiting\nWeakness or loss of sensation in the arms and\/or legs\nSpeech, vision, or memory problems\nPersonality changes\n\nHow Glioblastoma Is Treated\nGlioblastoma tumors contain a variety of cells, making them particularly difficult to treat. As a result, people diagnosed with glioblastoma may have to undergo a combination of treatments, including radiation, chemotherapy, and surgery.\nDoctors can identify glioblastomas using imaging studies, including MRIs and CT scans.