Note: As of December 2022, UPMC will now refer to “monkeypox” as “mpox.” This decision comes after recommendations from the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC).
The infectious disease mpox, formerly known as monkeypox, began spreading globally in the spring of 2022. The disease’s spread included the United States.
In July 2022, the World Health Organization (WHO) labeled mpox a “public health emergency of international concern.” U.S. health officials followed suit, declaring mpox a federal public health emergency in August 2022.
The Centers for Disease Control and Prevention (CDC) is monitoring the mpox outbreak in the United States. Before the 2022 outbreak, mpox was rare in the U.S.
The mpox virus is from the same virus family as the virus that causes smallpox. Mpox symptoms are similar to smallpox symptoms but are generally less severe, and the disease is typically not fatal.
Learn more about mpox, including symptoms and how it spreads.
What Is Monkeypox (Mpox)?
Mpox is a viral zoonosis, meaning it is a virus that passes from animals to humans. It causes a disease that creates similar symptoms to smallpox but is less severe overall. You can get mpox through contact with an infected animal or person.
Knowledge of mpox dates to 1958, when there were two outbreaks found in colonies of research monkeys.
Usually, the mpox virus is found in animals indigenous to western and central Africa. Until the current outbreak, it has spread between people but not widely and rarely in multiple countries.
But in May 2022, countries around the world began reporting much higher case numbers than normal. As of July 2022, the WHO reported mpox cases in 75 countries and territories across the world. That includes many countries that had never seen the disease before.
Many cases are occurring in Europe. These cases were the first reported in Europe without a known link to Africa, according to the European Centre for Disease Prevention and Control.
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How Does Monkeypox (Mpox) Spread?
You can get mpox through contact with an infected animal or person, according to the CDC. Mpox can enter your body through broken skin, through your respiratory tract, or through your eyes, nose, or mouth.
The virus can spread from the start of symptoms until a rash fully heals. That can be anywhere from two to four weeks. People without symptoms can’t spread the virus to others.
Many of the cases in the current mpox outbreak involve men who had sexual contact with other men. But anyone can get mpox.
According to the CDC, the most common methods for person-to-person spread include:
- Direct contact with an infected person’s rash, scabs, or bodily fluids.
- Respiratory secretions during prolonged face-to-face contact or during intimate physical contact (kissing, cuddling, or sex).
- Touching infected items like clothing or linens.
- From a pregnant mother to a fetus through the placenta.
The risk of transmission is generally low. Most human-to-human transmission happens through direct contact with pox lesions. Mpox can also spread by respiratory droplets, which requires prolonged face-to-face contact.
You can get mpox from contact with infected animals, too. This includes getting scratched or bitten, preparing or eating infected meat, or using products from an infected animal.
What Are the Symptoms of Monkeypox (Mpox)?
Mpox symptoms are similar to smallpox but usually less severe. Mpox is typically not fatal.
A rash appears in nearly everyone who contracts a mpox infection. Before the rash appears, some people have flu-like symptoms such as:
- Muscle aches.
- Swollen lymph nodes.
- Back pain.
The rash appears within a few days of flu-like symptoms. The WHO says symptoms usually appear within six to 13 days after being exposed. However, it could take more or less time for symptoms to appear.
The rash usually goes through several stages — spots, bumps, fluid- and then pus-filled pox lesions, and finally scabs — before falling off. It can appear on your face, inside your mouth, or on other areas of your body like your hands, feet, chest, genitals, or anus. However, some people only develop a rash in a small area and some only have bumps or pox-filled lesions.
Symptoms usually last for two to four weeks.
Is Monkeypox (Mpox) Treatable?
Mpox is often mild enough to not need treatment. There is no specific treatment for mpox. Because smallpox and mpox are similar, some treatments for smallpox may be effective against mpox.
Talk to your doctor about treatment options if you have symptoms of mpox.
Can I Prevent Monkeypox (Mpox)?
Vaccines to prevent mpox are not available to the general public at this time. There are two vaccines, ACAM2000 and JYNNEOS, that people who are exposed to mpox can get up to 14 days after exposure. If given within four days of exposure, the vaccine may prevent infection. If given within four to 14 days, it may help prevent severe symptoms.
Mpox vaccines may be available to eligible, at-risk individuals through state or local health departments or health providers.
UPMC received a very limited supply of the vaccine. The vaccine is going to patients who are eligible according to public health criteria. That includes patients who were exposed, patients with severe symptoms, and/or patients who are at risk for severe disease.
You cannot directly schedule a vaccine. Call your doctor or the local health department if you were exposed to mpox and/or you have symptoms.
UPMC will continue to follow guidelines from the Centers for Disease Control and Prevention (CDC), Pennsylvania Department of Health, and Allegheny County health officials for providing vaccinations. For more information, check the Allegheny County Health Department website or the Centers for Disease Control and Prevention (CDC) website.
If you have had prolonged contact with someone who has or is suspected of having mpox, contact your doctor or your local or state health department to see if you are eligible for vaccination. Monitor yourself for symptoms. If symptoms develop, you should self-isolate and call your doctor or the health department for guidance.
Besides vaccination, you can protect yourself by avoiding prolonged contact with people or animals who are suspected of having mpox.
Health care workers and household members of people with mpox may be at greater risk. They should take greater precautions, including using personal protective equipment (PPE) and maintaining good hand hygiene.
Should I Be Worried About Monkeypox (Mpox)?
Mpox cases are generally mild and go away within a few weeks. Stay home if you are sick, and avoid close contact with anyone who is sick, including people with an unknown rash.
If you are sick, you should isolate yourself until your rash is completely healed. Wear a facemask that covers your mouth and nose and cover your rash any time you are around others.
As with any emerging health condition, you should stay up to date on the latest information. Follow sources like the CDC, FDA, and your local and state health officials for updated guidance.
At UPMC, we are committed to providing the latest information as this story continues to develop.
Editor's Note: This article was originally published on , and was last reviewed on .
BBC, What Is Monkeypox, and How do You Catch It? Link
Centers for Disease Control and Prevention, Monkeypox. Link
European Centre for Disease Prevention and Control, Epidemiological Update: Monkeypox. Link
Daniel Victor, The New York Times, What to Know About Monkeypox. Link
World Health Organization, Monkeypox. Link
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