If you have ever received a vaccination, you know your arm may feel a bit sore for a few days after the fact.\nThe pain you are experiencing is usually soreness of the muscle where the injection was given. This pain is also a sign that your immune system is making antibodies in response to the viruses in the vaccine.\nRELATED:\u00a0The First Year: Downloadable Vaccination Schedule for Babies\nPain After a Shot: Normal Site Reactions to Vaccines\nAccording to the Centers for Disease Control and Prevention (CDC), in most cases vaccine side effects are minor and go away within a few days. Side effects vary according to vaccine type, such as flu, shingles, or pneumonia. Generally mild side effects of vaccines may include:\n\nPain, redness, tenderness, or swelling at injection site\nFatigue\nHeadache\nItching at injection site\nNausea\nDizziness or fainting (most common in adolescents)\n\nIt is likely the combination vaccines, like diphtheria, tetanus, whooping cough (DTaP), that cause greater local reaction and the \u201cpain\u201d you experience with the vaccine.\nCan You Reduce Pain or Swelling After Vaccines?\n\nMake sure to move your arm around after the vaccine. If you try to keep too still, it may hurt more.\nTake a pain reliever for one or two days after receiving vaccination to help with soreness and swelling.\nRotate a warm pack on and off the injection site\nIf you\u2019re concerned about the redness and swelling, outline the area with a marker. If it increases in size or does not decrease after a few days, call your doctor.\n\n\nRELATED:\u00a0Why Should I Get A Flu Shot?\nWhen Should I Seek Help for Injection-Site Pain?\nAny injection site that continues to be problematic after 48 hours should be seen by your doctor immediately. Other symptoms that may warrant medical care:\n\nHigh fever following a vaccination\nSigns of an allergic reaction, which can include difficulty breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heartbeat, or dizziness.\n\nConcerned about pain, swelling, or soreness after your vaccine? Find a UPMC Urgent Care location near you.