If you have Erectile Dysfunction (ED), your doctor might suggest taking oral medicine, such as Cialis®, Viagra®, or Levitra®. But not all men can or want to take medicine for ED — health issues or other medications you take may prevent you from being a good candidate for medical therapy.
If oral medicines don’t work for you, penile injection therapy may be a good option.
Never Miss a Beat!
Subscribe to Our HealthBeat Newsletter!
Thank you for subscribing!
You can now select the specific newsletters you'd like to receive.
You are already subscribed.
Subscribe to more newsletters in our email preference center.
Sorry, an error occurred. Please try again later.
Get Healthy Tips Sent to Your Phone!
Types of Penile Injection Therapy
With injection therapy, you inject medicine directly into your penis before you want an erection. Alprostadil is one of the main ingredients in erectile dysfunction injections; it works by relaxing blood vessels and the smooth muscle of the penis, which increases blood flow.
There are different types of medicine that may be used for the injections, but the technique of penile injection for treating erectile dysfunction is the same:
Using a tiny needle and syringe, you insert medicine into the side of your penis, directly into the erectile tissue. Depending on how much medicine you use, your erection may last longer than 30 minutes. This therapy has a success rate of 70 to 80 percent. If you have low blood flow in your penis, it may not be effective.
Penile injections must be self-administered, meaning you inject them yourself. Your doctor will give you the first dose to teach you how to do it properly. If you’re not comfortable giving yourself an injection, this therapy may not be right for you. If you are unable to give yourself the injection, your sexual partner can learn to administer it for you.
Side Effects and Risks of Penile Injection Therapy
Consider these side effects and risks before deciding if injection therapy is right for you:
- Injection site reactions: You might experience pain in your penis and could develop bruising or scar tissue at the site of injection.
- Alcohol: The combination of alcohol and erectile dysfunction medicine — oral or injected — can lead to a serious drop in blood pressure.
- Prolonged erection: In a small percentage of men, injection therapy can result in an erection lasting four to six hours. In rare cases, it can result in priapism, an erection that lasts longer than six hours. If your erection lasts more than four hours, seek medical attention immediately as this can result in penile tissue damage and permanent erectile dysfunction.
- Cardiovascular risk: In general, men whose cardiovascular health isn’t stable enough to have sex shouldn’t use injection therapy.
There may be other side effects or contraindications, such as having sickle cell disease, that prevent you from using injection therapy.
To learn if you’re a candidate for penile injection therapy and to discover more options for treating erectile dysfunction, visit the Men’s Health Center or call 1-877-641-4636(4MEN) to make an appointment.
Connect with UPMC
About Men’s Health Center
The UPMC Men’s Health Center evaluates and treats conditions affecting men’s sexual and reproductive health. With years of clinical experience in male sexual medicine and surgery, our team has treated a wide variety of conditions and performed thousands of surgeries. We are dedicated to providing patients the highest level of quality care. Our providers understand the intimate nature of male sexual difficulties, and we will work to help you restore your normal level of sexual function in a comfortable, educational, and discreet environment.